sholio: sun on winter trees (Default)
Sholio ([personal profile] sholio) wrote2018-08-06 11:26 pm

Adequan

I feel like a late-night infomercial with this, but if you have an older dog who's starting to have hip and joint problems, see what your vet thinks about giving them Adequan injections.

It's a glucosamine-like drug that was developed for racehorses and then approved for dogs. It's not at all cheap, is the problem. You're looking at several hundred $$$ for a few months' supply.

But damn. The effects are amazing. Our dog is 14, and when we first started giving it to him last summer, he was starting to have a lot of trouble with stairs, and fell down a lot, and we were giving him the maximum dose of Rimadyl (doggie painkillers) and he still limped and was starting to have kidney damage from the painkillers besides. I had never heard of Adequan at that point and our vet didn't bring it up on their own, but I asked them if it's possible to give human glucosamine pills to a dog, and they suggested the injections instead.

It took awhile (a month, at least) to really start noticing improvement. But after a few months he was like a whole new dog. He's still clearly old; his hearing and vision are going, and I suspect he might be having some senility issues. But we've cut him back to half the dose of Rimadyl, he hardly limps at all, he doesn't struggle with stairs and loves going for walks with me again. He's not as energetic as he used to be, but he can still zip around when he wants to.

There's an initial series of 7 shots, one every few days, and then a maintenance injection once a month. You can either take them to the vet for the injections or do it yourself at home. We had them teach us how, and it's really easy and doesn't seem to bother the dog much at all.

There are also next to no side effects. It baffles me that they don't have a human version of this, because it's incredibly effective and the worst thing it can do, at least the worst thing I know about, is that it can lower their platelet count so they bleed and bruise more easily. I haven't noticed that with Lucky at all, but apparently stopping the drug is all it takes to resolve it. The internet tells me that it's not uncommon for veterinarians to self-medicate with it if they have arthritis. It just doesn't have FDA approval, and they're also still unsure if it's safe for cats.

But in dogs, it's a freaking miracle drug. At least it's given Lucky probably a good solid extra couple of years of good, active dog life. The vet told me they had another canine patient who was brought in to be euthanized, tried them on Adequan, and they're still around a couple of years later. It not only eases their pain, it literally helps their bodies rebuild damaged cartilage in the joints. I think it's well worth checking out, if you have an old dog with back end problems and can field the cost.
lilacsigil: 12 Apostles rocks, text "Rock On" (12 Apostles)

[personal profile] lilacsigil 2018-08-07 08:42 am (UTC)(link)
It is used in humans as a blood thinner - it's very similar to heparin. I don't know it if has been tested for arthritis in humans, though!
lunabee34: (Default)

[personal profile] lunabee34 2018-08-07 10:26 am (UTC)(link)
So glad your dog feels better!
sheron: RAF bi-plane doodle (Johns) (Default)

[personal profile] sheron 2018-08-07 12:53 pm (UTC)(link)
Yay for doggie!
leesa_perrie: Dog, called Bear, from Person of Interest, with chewed book in his mouth (Bear)

[personal profile] leesa_perrie 2018-08-07 01:01 pm (UTC)(link)
Wow, so glad it worked for Lucky!

You can buy the tablets in the UK as a supplement, though trials have had mixed results in humans, with placebos having as much success as the glucosamine in some trials, and in one trial exercises were far better for improving joint pain (though that was against a placebo). So, if I had joint pain, I'd want to get physiotherapy but also try the pills and see if they worked or not. Even if it's the placebo effect at work, that's better than being in pain as far as I'm concerned!

[personal profile] indywind 2018-08-07 01:44 pm (UTC)(link)
Thanks for this info!
monanotlisa: symbol, image, ttrpg, party, pun about rolling dice and getting rolling (Default)

[personal profile] monanotlisa 2018-08-07 05:49 pm (UTC)(link)
I don't mean to sound like one of Those Conspiracy Theorists*, but it's odd how medications that would mean less NSAID painkiller consumption don't seem to make it past the FDA in the United States. I've run into two different medications now that directly and immediately lower pain levels, one with zero side effects and one with extremely rare side effects, that remain unobtainable in this country but are easy to get elsewhere in the world, including the Western world.

* Inevitably, conspiracy-theoretical babble follows.
rachelmanija: (Default)

[personal profile] rachelmanija 2018-08-07 06:31 pm (UTC)(link)
Out of curiosity, what are they?

I don't think you need to be a conspiracy theorist to believe that many things in the US value profit over human life.
secretsolitaire: white flowers. (Default)

[personal profile] secretsolitaire 2018-08-10 03:01 am (UTC)(link)
I'd also like to know what they are! :)

Sholio, I don't have a dog -- yet -- but I'm noting this (and wishing I could get it for my own creaky joints...).

(Anonymous) 2018-11-04 03:11 pm (UTC)(link)
Thank you ever so much for this post. On the vet's advice, I just started my dog Bud on this last Friday. He's 12 and like you said, hurting and starting to have trouble with stairs - and my place has a lot of stairs! I wasn't sure how long before I'd know if it's working and how much it would help, but was willing to bite the bullet if it would make him more comfortable. When I told Sealie, she suggested I check out your post. Hopefully Bud will have similar results. Cindy