Bayou! It's a webcomic, annoyingly done in Flash which makes my mouse go all wonky if I'm trying to do anything else, but I shouldn't be because it is freakin' addictive and very awesome. It's also a WIP, but I'm really impressed:

Bayou
http://www.zudacomics.com/node/112

It's going to be published in print and I'll definitely be buying it.

Also, the flash thing can't be blamed on the creator but on Zuda Comics, which I suspect does it in order to minimize downloading.